CLINICAL STUDIES ON COPPER PROTEIN

Studies on Copper Metabolism*

The results of studies on certain enzymes, hemin chromoproteins, and iron and copper in the tissues of normal, copper-deficient, and iron-deficient swine are reported in this paper. It has been suggested that the enzymes cytochrome oxidase (l-3), uricase (4), tyrosinase (5), plasma polyphenol oxidase (coeruloplasmin) (6), glutathione oxidase (7), and butyryl coenzyme A dehydrogenase (8) either ...

Studies on copper metabolism. XXXI. Erythrocyte copper.

Studies on Copper Metabolism. Xix

Ferrokinetic studies were performed in three copper-deficient swine and the results have been compared with similar studies in 18 normal pigs. The mean value for the plasma iron turnover rate in the deficient swine was 1.76 mg./kg. day; for the red cell iron incorporation rate, 1.24 mg./kg. day; for the red cell iron turnover rate, 1.18 mg./kg. day; for the red cell life span, 13 days. Correspo...

Structural studies on copper-containing plant oxidases.

Introduction Ascorbic acid oxidase (AAO) is ;I blue multi-copper oxidase that catalyses the four-electron reduction of dioxygen to water with concomitant one-electron oxidation of tlie reducing organic substrate [ 1 1. Copper-dependent A A O is found only in higher plants 12 I. The enzyme from Cucurbitu pep0 medullosa (green zucchini) is ;I dimer of 14OOOO-M,. containing eight copper ions of th...

Clinical studies on progressive retinal atrophy in 31 dogs

During a 2-year period, 31 cases of a hereditary retinal degeneration in dogs bred in India were found mainly suspected for progressive retinal atrophy (PRA) with typical history of initial nyctalopia followed by hemeralopia. Out of 31 PRA suspected dogs, 8 dogs (26%) were from the age group of 1-5 years, 15 (48%) 6-10 years and the rest (26%) 11-15 years. The most predominant breed was Spitz (...